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Trimethoprim/Sulfamethoxazole (Bactrim)

160/800 mg DS

Antibiotic18+

Stop: Call 911 or get emergency help

Trouble breathing or lip/tongue swelling; fainting; severe rash with blisters, peeling, or sores; skin redness spreading fast; yellow skin/eyes; very weak/dizzy or pounding/uneven heartbeat; shaky, sweaty, or confused.

Seek medical help first

Use this information only if you are unable to contact your provider. Then, contact your provider as soon as possible.

What it may treat & how much to take

  1. 1

    Bladder infection (UTI) in a woman

    Burning or urgency; frequent small pees; lower-belly pressure; cloudy/smelly urine. No fever or back pain.

    Take 1 tablet twice a day for 3 days. Provider may also prescribe phenazopyridine (see card).

  2. 2

    Kidney infection

    UTI signs + fever/chills, shaking, one-sided lower-back pain, or nausea.

    Take 1 tablet twice a day for 7 days. Get medical care ASAP.

  3. 3

    Skin infection / mild cellulitis

    Skin is red, warm, swollen and tender; no pus, boil or abscess.

    See amoxicillin/clavulanate card.

  4. 4

    Skin infection with pus / abscess

    Red, warm, swollen, tender skin with pus or drainage.

    Seek medical care; needs to be drained. After drained: a provider may prescribe 1 tablet twice a day for 5–7 days, OR doxycycline (see card).

How to take it

Take with food and a full glass of water; drink plenty of water all day. Take doses about 12 hours apart. Finish the full course, even if you feel better. Limit sun; wear a hat, long sleeves, and sunscreen.

Important information

Get medical care if not better in 3 days, symptoms worsen, a UTI adds fever/chills/back pain, or skin redness spreads fast.

Common side effects

Upset stomach/nausea, vomiting, low appetite, loose stools, headache.

Do not take if

You have a trimethoprim/sulfamethoxazole allergy; severe liver or kidney disease, low-folate megaloblastic anemia or G6PD deficiency; or take dofetilide or methotrexate unless a doctor specifically tells you otherwise.

Ask your provider or pharmacist first if

You take warfarin; lisinopril, losartan, spironolactone or potassium; diabetes pills; phenytoin; or have porphyria or thyroid disease.

If pregnant or breastfeeding

Do not take trimethoprim/sulfamethoxazole from the kit until a doctor says it is safe.

Educational reference only. Contents, availability, and clinical eligibility vary. A prescription is issued only when clinically appropriate. This information is not medical advice.