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Ciprofloxacin (Cipro)

500 mg

Antibiotic18+

Stop: Call 911 or get emergency help

Trouble breathing or face/tongue swelling; seizure or thoughts of self-harm; fainting/fast uneven heartbeat; sudden severe chest, belly, or back pain; or severe confusion.

Seek medical help first

Use this information only if you are unable to contact your provider. Then, contact your provider as soon as possible.

What it may treat & how much to take

  1. 1

    Severe traveler's diarrhea

    Many watery stools/cramps/weakness that stop normal activity. No blood/fever; if either, azithromycin is preferred.

    Ciprofloxacin backup: Take 1 tablet twice a day for 3 days.

  2. 2

    Bladder infection (UTI) — backup

    Burning when you pee; frequent or urgent urination; cloudy or smelly urine; pain above pubic bone. No fever or back pain.

    If you cannot use nitrofurantoin or trimethoprim/sulfamethoxazole, take ½ tablet twice a day for 3 days.

  3. 3

    Kidney infection

    Bladder infection signs plus fever or chills, pain in one side or lower back, nausea, or vomiting.

    Take 1 tablet twice a day for 7 days. Get medical care.

  4. 4

    Diverticulitis

    Only if diagnosed before: steady lower-left belly pain with fever/chills, nausea, bowel changes and tender belly.

    Take 1 tablet twice a day PLUS metronidazole 1 tablet 3 times a day for 7–10 days. Contact your provider immediately.

  5. 5

    Serious belly infection after a gut injury

    Bad belly pain with fever/chills; belly tender to touch.

    Take 1 tablet twice a day PLUS metronidazole 1 tablet 3 times a day for 7–10 days. Get medical care right away.

How to take it

Take with food and plenty of water, about 12 hours apart. Take 2 hours before or 6 hours after antacids or vitamins with calcium, iron, zinc, or magnesium. Limit caffeine and avoid strong sun.

Important information

Do not do heavy exercise. Stop and get care for tendon pain, numbness/tingling, confusion, severe anxiety/depression, bad headache, seizure, sudden severe chest/belly/back pain, severe rash, yellow skin/eyes, worsening diarrhea, fainting, or blood-sugar symptoms.

Common side effects

Nausea, loose stools, vomiting, headache, trouble sleeping.

Do not take if

Allergy to ciprofloxacin or another -floxacin antibiotic; you take tizanidine; or you have myasthenia gravis.

Ask your provider or pharmacist first if

You have tendon problems; use prednisone; are over 60; have kidney, seizure/nerve, heart rhythm problems, diabetes, aneurysm, or high blood pressure. Ask before combining with ondansetron, azithromycin, fluconazole, or loperamide.

If pregnant or breastfeeding

Avoid ciprofloxacin; call a provider first. Do not breastfeed during treatment or for 2 days after the last dose.

Educational reference only. Contents, availability, and clinical eligibility vary. A prescription is issued only when clinically appropriate. This information is not medical advice.